Table 1 Correlation between COX-2, VEGF-C, peritumoral LVD and clinicopathologic factors in gastric carcinoma
Parameters | N | COX-2 expression | VEGF-C expression | LVD | |||||
|---|---|---|---|---|---|---|---|---|---|
|  |  | Low | High | P value | Low | High | P value | Mean ± SD | P value |
Histological grading | |||||||||
   Low | 34 | 11 | 23 | 0.916 | 16 | 18 | 0.703 | 9.03 ± 4.37 | 0.721 |
   Moderate | 18 | 5 | 13 |  | 8 | 10 |  | 9.88 ± 5.15 |  |
   Well | 4 | 1 | 3 |  | 1 | 3 |  | 8.14 ± 2.69 |  |
Depth of invasion | |||||||||
   T1+T2 | 36 | 12 | 24 | 0.516 | 17 | 19 | 0.602 | 8.37 ± 3.85 | 0.052 |
   T3+T4 | 20 | 5 | 15 |  | 8 | 12 |  | 10.80 ± 5.24 |  |
Lymph node metastasis | |||||||||
   No | 17 | 5 | 12 | 0.919 | 10 | 7 | 0.159 | 6.64 ± 3.01 | 0.003 |
   Yes | 39 | 12 | 27 |  | 15 | 24 |  | 10.37 ± 4.61 |  |
TNM stage | |||||||||
   I+ II | 34 | 11 | 23 | 0.686 | 18 | 16 | 0.12 | 8.40 ± 3.95 | 0.084 |
   III+IV | 22 | 6 | 16 |  | 7 | 15 |  | 10.53 ± 5.08 |  |