Enhancive effects of Lewis y antigen on CD44-mediated adhesion and spreading of human ovarian cancer cell line RMG-I

Table 2 HA-mediated adhesion and spreading of RMG-I and RMG-I-H cells

	Cell adhesion		Cell spreading
Group	RMG-I	RMG-I-H	RMG-I	RMG-I-H
Lewis y antibody-untreated	1.41 ± 0.20	2.57 ± 0.58*	34 ± 5	57 ± 6*
Lewis y antibody-treated	0.53 ± 0.03**	0.76 ± 0.27**	16 ± 5**	14 ± 4**
Irrelevant isotype-matched control	1.36 ± 0.15	2.44 ± 0.67	35 ± 6	59 ± 8

* P < 0.01, vs. RMG-I cells; ** P < 0.01, vs. Irrelevant isotype-matched control.

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