Characteristics | Patients (n = 41) | LgR5 Barrett's esophagus* | p-value | LgR5 Barrett's EAC | p-value | ||
---|---|---|---|---|---|---|---|
 |  | low | high |  | low | high |  |
Age (y) | Â | Â | Â | .100 | Â | Â | .051 |
<66 | 21 (51%) | 10 (48%) | 11 (52%) | Â | 4 (19%) | 17 (81%) | Â |
≥66 | 20 (49%) | 4 (20%) | 16 (80%) |  | 10 (50%) | 10 (50%) |  |
Gender | Â | Â | Â | .074 | Â | Â | .673 |
Male | 34 (83%) | 14 (41%) | 20 (59%) | Â | 11 (32%) | 23 (68%) | Â |
Female | 7 (17%) | 0 (0%) | 7 (100%) | Â | 3 (43%) | 4 (57%) | Â |
Histological Grading | Â | Â | Â | .305a | Â | Â | .083a |
G1 | 11 (27%) | 6 (55%) | 5 (45%) | Â | 6 (55%) | 5 (45%) | Â |
G2 | 16 (39%) | 5 (31%) | 11 (69%) | Â | 6 (37%) | 10 (63%) | Â |
G3/4 | 14(34%) | 3 (21%) | 11 (79%) | Â | 2 (14%) | 12 (86%) | Â |
Depth of invasion | Â | Â | Â | .481b | Â | Â | .155b |
pT1 | 10 (24%) | 4 (40%) | 6 (60%) | Â | 6 (60%) | 4 (40%) | Â |
pT2 | 18 (44%) | 7 (39%) | 11 (61%) | Â | 6 (33%) | 12 (67%) | Â |
pT3 | 6 (15%) | 1 (17%) | 5 (83%) | Â | 1 (17%) | 5 (83%) | Â |
pT4 | 7 (17%) | 2 (28%) | 5 (72%) | Â | 1 (14%) | 6 (86%) | Â |
Lymph node metastases | Â | Â | Â | .001 | Â | Â | .0154 |
pN0 | 15 (37%) | 10 (67%) | 5 (33%) | Â | 9 (60%) | 6 (40%) | Â |
pN1-3 | 26 (63%) | 4 (15%) | 22 (85%) | Â | 5 (19%) | 21 (81%) | Â |
UICC stage | Â | Â | Â | .481c | Â | Â | .155c |
UICC I | 9 (22%) | 4 (44%) | 5 (56%) | Â | 2 (22%) | 4 (78%) | Â |
UICC II | 19 (46%) | 7 (37%) | 12 (63%) | Â | 7 (37%) | 12 (63%) | Â |
UICC III | 13 (31%) | 3 (23%) | 10 (77%) | Â | 5 (15%) | 11 (85%) | Â |
UICC IV | 0 (0%) | 0 (0%) | 0 (0%) | Â | 0 (0%) | 0 (0%) | Â |
Median OS (m) | 42 m | 32 (n = 14) | 24 (n = 27) | Â | 33 (n = 14) | 28 (n = 27) | Â |