Table 1 Clinicopathological characteristics of the EAC study population with BE

low

high

low

high

Age (y)

.100

.051

<66

21 (51%)

10 (48%)

11 (52%)

4 (19%)

17 (81%)

≥66

20 (49%)

4 (20%)

16 (80%)

10 (50%)

10 (50%)

Gender

.074

.673

Male

34 (83%)

14 (41%)

20 (59%)

11 (32%)

23 (68%)

Female

7 (17%)

0 (0%)

7 (100%)

3 (43%)

4 (57%)

Histological Grading

.305^a

.083^a

G1

11 (27%)

6 (55%)

5 (45%)

6 (55%)

5 (45%)

G2

16 (39%)

5 (31%)

11 (69%)

6 (37%)

10 (63%)

G3/4

14(34%)

3 (21%)

11 (79%)

2 (14%)

12 (86%)

Depth of invasion

.481^b

.155^b

pT1

10 (24%)

4 (40%)

6 (60%)

6 (60%)

4 (40%)

pT2

18 (44%)

7 (39%)

11 (61%)

6 (33%)

12 (67%)

pT3

6 (15%)

1 (17%)

5 (83%)

1 (17%)

5 (83%)

pT4

7 (17%)

2 (28%)

5 (72%)

1 (14%)

6 (86%)

Lymph node metastases

.001

.0154

pN0

15 (37%)

10 (67%)

5 (33%)

9 (60%)

6 (40%)

pN1-3

26 (63%)

4 (15%)

22 (85%)

5 (19%)

21 (81%)

UICC stage

.481^c

.155^c

UICC I

9 (22%)

4 (44%)

5 (56%)

2 (22%)

4 (78%)

UICC II

19 (46%)

7 (37%)

12 (63%)

7 (37%)

12 (63%)

UICC III

13 (31%)

3 (23%)

10 (77%)

5 (15%)

11 (85%)

UICC IV

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

Median OS (m)

42 m

32 (n = 14)

24 (n = 27)

33 (n = 14)

28 (n = 27)