Skip to main content

Table 1 Cell viability with EPD treatment of normal fibroblasts, OVCAR3 and SKOV3 cancer cells (average (AV) and standard deviation (SD))

From: Potent cytotoxic effects of Calomeria amaranthoides on ovarian cancers

 

% cell viability: average and standard deviation

EPD Conc

24 hours

48 hours

72 hours

μg/mL

AV

SD

AV

SD

AV

SD

 

Normal fibroblasts

1

102

2.5

107

3.9

105

3.3

5

105

6.3

108

1.6

72

2.1

10

101

10.1

112

1.8

47

4.6

 

OVCAR 3

1

96

5.1

101

7.4

109

29.2

5

87

6.7

67

4.5

50

14.4

10

70

7.4

23

0.9

21

6.4

 

SKOV 3

1

103

5.0

123

8.2

119

6.0

5

102

4.0

96

18.2

69

16.5

10

86

11.6

31

36.0

23

1.8

  1. IC50 for OVCAR3 at 24 hours was 13 μg/mL (95% C.I. 10 to 18 μg/mL), at 48 hours 6.4 μg/mL (95% C.I. 5.3 to 7.8 μg/mL) and at 72 hours 5.3 μg/mL (95% C.I. 4.3 to 6.5 μg/mL).
  2. IC50 for SKOV3 at 24 hours was 16 μg/mL (95% C.I. 9.4 to 27 μg/mL), at 48 hours 8.4 μg/mL (95% C.I. 6.7 to 11 μg/mL) and at 72 hours 6.5 μg/mL (95% C.I. 5.2 to 8.3 μg/mL).