Table 2 Comparison of EGFR and KRAS status between primary and metastatic tumors in NSCLC patients
Case No. | EGFR mutation status | KRAS mutation status | ||
|---|---|---|---|---|
| Â | primary | metastasis | primary | metastasis |
1 | E746-A750 | L747-T751 | wt | wt |
2 | L747-P753insS | R748-P752 | wt | wt |
3 | wt | L747-P753 | wt | wt |
4 | wt | L858R | wt | wt |
5 | wt | L858R | wt | wt |
6 | wt | L858R | wt | wt |
7 | wt | L858R | wt | G12V |
8 | L858R | L858R | wt | G12A |
9 | wt | wt | wt | G12V |
10 | wt | wt | wt | G13D |
11 | wt | wt | wt | G12S |
12 | wt | wt | wt | G13D |
13 | E746-A750 | E746-A750 | wt | wt |
14 | E746-A750 | E746-A750 | wt | wt |
15 | E746-A750 | E746-A750 | wt | wt |
16 | E746-A750 | E746-A750 | wt | wt |
17 | E746-A750 | E746-A750 | wt | wt |
18 | E746-A750 | E746-A750 | wt | wt |
19 | E746-A750 | E746-A750 | wt | wt |
20 | L858R | L858R | wt | wt |
21 | L858R | L858R | wt | wt |
22 | L858R | L858R | wt | wt |
23 | L858R | L858R | wt | wt |
24 | L858R | L858R | wt | wt |
25 | L858R | L858R | wt | wt |
26 | L858R | L858R | wt | wt |
27 | L747-S752,P753E | L747-S752,P753E | wt | wt |
28 | E746-T751insV/A | E746-T751insV/A | wt | wt |
29 | E747-S752insV | E747-S752insV | wt | wt |
30 | I740-K745 | I740-K745 | wt | wt |
31 | wt | wt | G12A | G12A |
32 | wt | wt | wt | wt |
. | Â | |||
. | Â | |||
. | Â | |||
80 | wt | wt | wt | wt |