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Figure 4 | Journal of Experimental & Clinical Cancer Research

Figure 4

From: Anticancer activity of the iron facilitator LS081

Figure 4

Effect of LS081 on the proliferation of the prostate cancer cells and non-malignant prostate cells. Both prostate cancer cell line PC-3 and the immortalized, non-malignant prostate cell line 267B1 cells grown in serum-free RPMI1640 with 0.1% bovine serum albumin were treated with 0.1% DMSO or with 3 or 10 μM LS081 ± 2 μM ferric ammonium citrate for 24 hr followed by an additional 24 hr in RPMI1640-10% FCS before cell proliferation was assayed by MTS. The results are expressed as growth inhibition relative to the DMSO controls (means ± SEM of 3-4 independent observations with four replicates in each observation). *: P < 0.05, **: P < 0.01 comparing with or without Fe conditions by 2-way ANOVA with Bonferroni's posttests.

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