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Table 1 Characteristics of treatment in each group of rats.

From: Comparison of hyperthermia and adrenaline to enhance the intratumoral accumulation of cisplatin in a murin model of peritoneal carcinomatosis

Group

Cisplatin

Adrenaline

Temperature

Duration of treatment

1

30 mg/ml

No

37°C

1 h

(1 bis*)

30 mg/ml

2 mg/l

37°C

1 h

2

30 mg/ml

No

42°C

1 h

3

30 mg/ml

2 mg/ml

37°C

2 h (twice 1 hour)

4

30 mg/ml

No

37°C

2 h (twice 1 hour)

  1. (*) In another experiment group 1 bis achieved the same tissue concentration of cisplatin as group 1 (unpublished data), thus this group was not repeated in the present study