Comparison of hyperthermia and adrenaline to enhance the intratumoral accumulation of cisplatin in a murin model of peritoneal carcinomatosis

Table 1 Characteristics of treatment in each group of rats.

Group	Cisplatin	Adrenaline	Temperature	Duration of treatment
1	30 mg/ml	No	37°C	1 h
**(1 bis)***	30 mg/ml	2 mg/l	37°C	1 h
2	30 mg/ml	No	42°C	1 h
3	30 mg/ml	2 mg/ml	37°C	2 h (twice 1 hour)
4	30 mg/ml	No	37°C	2 h (twice 1 hour)

(*) In another experiment group 1 bis achieved the same tissue concentration of cisplatin as group 1 (unpublished data), thus this group was not repeated in the present study

ISSN: 1756-9966