Table 3 Significant Toxicities results
Toxicity | Pts (RCTs) | RR (95% CI) | p-value | Het. (p) | AD (%) | NNH |
|---|---|---|---|---|---|---|
Hypertension | 3,841 (5) | 5.15 (1.60, 16.6) | 0.006 | < 0.0001 | 4.5 | 22 |
Proteinuria | 3,841 (5) | 9.55 (3.44, 26.5) | < 0.0001 | 0.96 | 0.4 | 250 |
Neurotoxicity | 3,379 (4) | 1.20 (1.01, 1.43) | 0.044 | 0.61 | 2.6 | 39 |
Febrile Neutropenia | 3,379 (4) | 1.39 (1.07, 1.83) | 0.015 | 0.60 | 2.1 | 46 |
Bleeding | 3,841 (5) | 3.05 (1.13, 8.23) | 0.028 | 0.56 | 0.6 | 175 |