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Table 3 Univariate logistic regression analysis: Significant association between expression of STAT3 and pSTAT3 and clinicopathological characteristics of soft tissue tumors.

From: Prognostic significance of STAT3 and phosphorylated STAT3 in human soft tissue tumors - a clinicopathological analysis

Clinicopathological characteristics

STAT3

pSTAT3

 

OR

95% CI

P-value

OR

95% CI

P-value

Grade of tumor

      

   Benign or intermediate

1

  

1

  

   Malignant

107.3

20.24-569

< 0.001

7.5

2.28-24.5

0.001

Tumor Size

      

   < = 5 cm

1

  

1

  

   >5 & < = 10 cm

2.42

0.78-7.45

0.123

1.96

0.58-6.57

0.276

   >10 & < = 15 cm

19.38

2.25-166.5

0.007

1.71

0.43-6.71

0.439

   >15 cm

2.7

0.58-13.16

0.2

4.57

1.18-17.68

0.028

Tumor Location

      

   Upper limb

1

  

1

  

   Lower limb

4

1.05-15.2

0.042

9

1.05-77.03

0.045

   Thorax

1.6

0.37-6.8

0.525

3.4

0.34-34.99

0.299

   Head & neck

1.6

0.08-31.7

0.758

   

   Retroperitoneum

9.6

1.48-62.15

0.018

16

1.6-159.3

0.018

Plane of Tumor

      

   Subcutis

1

  

1

  

   Muscular plane

4.14

1.3-13.2

0.016

4.01

1.31-12.32

0.015

   Body cavity

8.05

1.62-39.8

0.011

5.6

1.6-19.6

0.007

Circumscription

      

   No

1

  

1

  

   Yes

0.2

0.07-0.55

0.002

1.005

0.40-2.5

0.991

Necrosis

      

   No

1

  

1

  

   Yes

18.13

2.28-143.6

0.006

4.98

1.7-14.3

< 0.001