Figure 1

Toxicity of BSO on HepG2 cells. Under normoxic or hypoxic condition, HepG2 cells were treated with different concentration of BSO for 12 h before subjected to the MTT assay. The viability was calculated by subtracting the background absorbance and divided by the control absorbance. Both normoxia and hypoxia, the results showed that there was not significance in the decrease of cells viability until the concentration of BSO was at 400 μM. The change of cells viability, under normoxia or hypoxia, was displayed in Diagram A and Diagram B respectively.