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Table 2 Genes expression of TAM in relationship with clinicopathological factors

From: Increased IL-10 mRNA expression in tumor-associated macrophage correlated with late stage of lung cancer

   IL-10 Cathepsin B
Variables N Median(Range) p * value Median (Range) p * value
age      
   <58 26 31.3(3.05-530.3) 0.252 10.9(0.9-51.9) 0.41
   ≥58 37 30.5(0.6-511.6)   14.5(0.6-69.1)  
Gender      
   Male 40 31.3(1.3-530.3) 0.607 14.9(0.9-69.1) 0.061
   Female 23 19.9(0.6-426.1)   10.1(0.6-37.9)  
Smoking history      
   Never 29 30.5(0.6-426.1) 0.699 10.1(0.6-51.9) 0.067
   Former or current 34 31.2(1.3-530.3)   14.9(1.5-69.1)  
Histology      
   Adenocarcinoma 34 42.9(0.6-530.3) 0.045 12.7(0.6-69.1) 0.41
   Squamous cell carcinoma 20 17.1(1.3-354.3)   16.6(1.5-41.7)  
   Others 9 41.2(6.4-511.6)   10.2(4.2-26.7)  
Pathological stage      
   Stage I 30 9.7(0.6-140.8) 0.016 13.1(0.6-69.1) 0.066
   StageII 11 28.9(1.8-511.6)   13.6(3.1-41.7)  
   StageIII 17 177.7(23.5-530.3)   11.8(1.2-51.9)  
   StageIV 5 249.9(55.4-429.9)   10.1(3.6-25.9)  
T status      
   T1 15 4.1(0.6-263.6) <0.0001 9.9(0.6-22.7) 0.037
   T2-3 48 42.9(1.6-530.3)   14.2(0.9-69.1)  
Lymph node metastasis      
   N(+) 21 119.1(6.1-530.3) <0.0001 13.6(1.2-46.9) 0.466
   N(-) 42 19.2(0.6-273.8)   11.1(0.6-69.1)  
Lymphovascular invasion      
   LVI(+) 12 93.1(6.2-530.3) 0.01 14.2(0.9-37.8) 0.92
   LVI(-) 51 26.5(0.6-429.9)   11.1(0.6-69.1)  
Pleural invasion      
   PL(+) 20 55.8(14.9-530.3) 0.002 14.2(0.9-69.1) 0.376
   PL(-) 43 19.9(0.6-354.9)   11.1(0.6-51.9)  
Differentiation      
   Well or Moderately 30 17.3(0.6-429.9) 0.001 13.0(0.6-69.1) 0.961
   poorly 26 113.1(1.6-530.3)   11.9(1.2-37.9)  
  1. *p by the Mann-Whitney U test