Figure 4

IT anti-c-Met/PE38KDEL inhibited tumor cell growth through induction of apoptosis. To measure the dose response effect of IT on cell apoptosis rate of GES-1, MKN-45 and SGC7901, cells were treated with different concentrations of anti-c-Met/PE38KDEL. Cells were incubated with IT at 0, 10 and 50 ng/ml for 24 hr, and the percentage of cell apoptosis was determined by flow cytometry. IT induced apoptosis for its anticancer effect.