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Figure 1 | Journal of Experimental & Clinical Cancer Research

Figure 1

From: Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma

Figure 1

Effects of statins on C6 glioma cell proliferation and viability. (A-C) C6 glioma cells were incubated at a concentration of 2 × 104 cells/ml for 24 h in a 96-well plate. These cells were treated with various concentrations of statins. After incubation for 24, 48, or 72 h, the number of viable cells was counted by trypan blue staining. The results are representative of 5 independent experiments. *p < 0.01 vs. controls (ANOVA with Dunnett's test). (D-F) C6 glioma cells were treated with various concentrations of statins and trypan blue exclusion test was performed after 24, 48, or 72 h. The results are representative of 5 independent experiments. *p < 0.01 vs. controls (ANOVA with Dunnett's test).

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