Effect of CDKN2A on cell growth. CDKN2A reduced the growth of U87-MG (A) and SW1738 (B) glioma cell lines. U87-MG and SW1738 were transfected with pCDNA 3.1 vector and CDKN2A respectively. A mixed clones cells were obtained after G418 (800 μg/ml) selection for 1 week. Growth curve experiment was performed. The results were present by mean ± SD. * P < 0.05, **P < 0.01 (Student's t-test) in all cases. All experiments were performed in triplicate.