Figure 3
From: HIF-1α effects on angiogenic potential in human small cell lung carcinoma
Growth of the transplantation tumor. The growth curves of the transplantation tumors in the three groups are shown. Data are presented as means ± SD. (A) The growth curves of transplantation tumors in the NCI-H446/HIF-1α group shifted left, and the growth curves shifted right in the Ad5-siHIF-1α group (*p < 0.01 represents NCI-H446/HIF-1α group vs. NCI-H446 group; **p < 0.01 represents NCI-H446/siHIF-1α group vs. NCI-H446 group). (B) A transplantation tumor from the NCI-H446 group (10 d after implantation). (C) A transplantation tumor from the NCI-H446/HIF-1α group (10 d after implantation). (D) A transplantation tumor from the NCI-H446/siHIF-1α group (10 d after implantation). (E) A transplantation tumor from the NCI-H446/Ad5 group (10 d after implantation). (F) A transplantation tumor from the NCI-H446/Ad5-siRNA group (10 d after implantation). (G) Comparing to the growth curves in NCI-H446 group the tendency of the curves in NCI-H446/Ad5 group and NCI-H446/Ad5-siRNA group had no significant changes. (*p > 0.05 represents NCI-H446 group vs. NCI-H446/Ad5 group; **p > 0.01 represents NCI-H446/Ad5-siRNA group vs. NCI-H446 group).