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Table 2 Expression of Hh and its receptors in CML-CP patients with IM administered or not

From: Activation of the hedgehog pathway in chronic myelogeneous leukemia patients

CML-CP n Expression
level(°C ± S)
P value
Shh    
   Without Imatinib 7 0.55 ± 0.020 0.24
   With Imatinib 31 0.46 ± 0.017  
Ptch1    
   Without Imatinib 7 1.21 ± 0.031 0.12
   With Imatinib 31 0.87 ± 0.031  
Smo    
   Without Imatinib 7 0.66 ± 0.020 0.88
   With Imatinib 31 0.59 ± 0.023  
Gli1    
   Without Imatinib 7 0.83 ± 0.042 0.43
   With Imatinib 31 0.73 ± 0.027