Activation of the hedgehog pathway in chronic myelogeneous leukemia patients

Table 2 Expression of Hh and its receptors in CML-CP patients with IM administered or not

CML-CP	n	Expression level(°C ± S)	P value
Shh
Without Imatinib	7	0.55 ± 0.020	0.24
With Imatinib	31	0.46 ± 0.017
Ptch1
Without Imatinib	7	1.21 ± 0.031	0.12
With Imatinib	31	0.87 ± 0.031
Smo
Without Imatinib	7	0.66 ± 0.020	0.88
With Imatinib	31	0.59 ± 0.023
Gli1
Without Imatinib	7	0.83 ± 0.042	0.43
With Imatinib	31	0.73 ± 0.027

ISSN: 1756-9966