Skip to main content

Table 1 Association of NF-κB and Notch1 expression with clinical characteristics

From: Different patterns of NF-κB and Notch1 signaling contribute to tumor-induced lymphangiogenesis of esophageal squamous cell carcinoma

Clinicopathological feature NF-κB expression P- value Notch1 expression P-value
  High Low   High Low  
Gender       
  Male 21 25 0.451 22 24 0.887
  Female 8 6   7 7  
Age (years)       
  ≤ 60 17 23 0.201 23 17 0.058
  > 60 12 8   6 14  
Differentiation       
  Well 7 8 0.231 3 12 0.001
  Moderate 16 11   10 17  
  Poor 6 12   16 2  
TNM stages       
  I + II 8 12 0.361 10 10 0.855
  III 21 19   19 21  
Lymphatic metastasis       
  With 23 2 0.001 6 19 0.001
  Without 6 29   23 12  
LVD (VEGF-R3)       
  High 19 12 0.038 10 21 0.010
  Low 10 19   19 10  
Podoplanin       
  High 20 10 0.004 8 19 0.008
  Low 9 21   21 12  
VEGF-C expression       
  High 18 11 0.039 6 23 0.001
  Low 11 20   23 8  
Notch1 expression       
  High 8 21 0.002    
  Low 10 21