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Table 1 Association of NF-κB and Notch1 expression with clinical characteristics

From: Different patterns of NF-κB and Notch1 signaling contribute to tumor-induced lymphangiogenesis of esophageal squamous cell carcinoma

Clinicopathological feature

NF-κB expression

P- value

Notch1 expression

P-value

 

High

Low

 

High

Low

 

Gender

      
 

Male

21

25

0.451

22

24

0.887

 

Female

8

6

 

7

7

 

Age (years)

      
 

≤ 60

17

23

0.201

23

17

0.058

 

> 60

12

8

 

6

14

 

Differentiation

      
 

Well

7

8

0.231

3

12

0.001

 

Moderate

16

11

 

10

17

 
 

Poor

6

12

 

16

2

 

TNM stages

      
 

I + II

8

12

0.361

10

10

0.855

 

III

21

19

 

19

21

 

Lymphatic metastasis

      
 

With

23

2

0.001

6

19

0.001

 

Without

6

29

 

23

12

 

LVD (VEGF-R3)

      
 

High

19

12

0.038

10

21

0.010

 

Low

10

19

 

19

10

 

Podoplanin

      
 

High

20

10

0.004

8

19

0.008

 

Low

9

21

 

21

12

 

VEGF-C expression

      
 

High

18

11

0.039

6

23

0.001

 

Low

11

20

 

23

8

 

Notch1 expression

      
 

High

8

21

0.002

   
 

Low

10

21