Figure 4

AQP3 regulated PI3K/AKT pathway in SGC7901 cells. AQP3 silence blocked PI3K/AKT pathway in SGC7901 cells. AQP3 silence led to a significant decrease in phosphorylation of ser473 in AKT. * p<0.05 BLANK control SGC7901 cells NC cells treated with scrambled shRNA aqp3shRNA cells treated with aqp3shRNA