Hypersensitivity reactions to anticancer agents: Data mining of the public version of the FDA adverse event reporting system, AERS

Table 1 The number of adverse events occurring with each anticancer agent

	N ^a)	Mild ^b)	Severe ^b)	Lethal ^b)
paclitaxel	42,038	228 *	79 *	12 *
docetaxel	36,983	79	18	17 *
procarbazine	1,287	1	0	0
asparaginase	6,414	1	5	2
teniposide	151	1	0	0
etoposide	28,264	31	25	3
doxorubicin	47,834	101	41	9
6-mercaptopurine	9,170	17	13	0
5-fluorouracil	40,282	108 *	44	10 *
cyclophosphamide	70,728	110	51	9
cytarabine	31,765	20	24	3

a) the total number of adverse events occurring with each anticancer agent.
b) the number of co-occurrences of mild, severe and lethal hypersensitivity reactions.
*: A signal was detected by at least 1 of 4 statistical indices

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