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Table 1 Demographic/clinicopathologic characteristics and clinical outcome after treatment with a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in 49 Japanese patients with esophageal squamous cell carcinoma

From: Effects of plasma concentrations of 5-fluorouracil on long-term survival after treatment with a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma

Group

Total

Survival of 5 years or more

Survival of less than 5 years

P a)

N

49

21

28

 

1) Demographic/clinicopathologic

    

   Age, yr

64.5 ± 7.4 (48 -78) b)

67.3 ± 5.8 (60 -78)

62.4 ± 7.9 (48 -76)

0.020

   Height, cm

163.5 ± 6.6 (150-180)

161.9 ± 6.1 (150-171)

164.8 ± 6.8 (152-180)

0.125

   Weight, kg

56.1 ± 9.6 (33-79)

59.8 ± 9.5 (40-74)

53.3 ± 8.9 (33-79)

0.019

   Male/Female

46/3

20/1

26/2

1.000

   Performance status, 0/1/2/unknown

24/20/4/1

11/7/2/1

13/13/2/0

0.579

   Differentiation, well/moderate/poor/unknown

7/28/8/6

4/11/3/3

3/17/5/3

0.817

   T1/T2/T3/T4

16/6/15/12

10/2/7/2

6/4/8/10

0.099

   N0/N1

22/27

13/8

9/19

0.048

   M0/M1a c)

41/8

20/1

21/7

0.115

   Stage I/II/III/IV

12/10/19/8

7/7/6/1

5/3/13/7

0.048

2) Clinical outcome

    

   Complete response

23 (46.9%)

16 (76.2%)

7 (25.0%)

0.0005

   Grade 3/4 Leucopenia

21(42.9%)

9 (42.9%)

12 (42.9%)

1.000

   Grade 3/4 Stomatitis

7 (14.3%)

4 (19.0%)

3 (10.7%)

0.443

   Grade 3/4 Cheilitis

8 (16.3%)

4 (19.0%)

4 (14.3%)

0.710

  1. a) Survival of 5 years or more vs. less than 5 years.
  2. b) The values are the mean ± SD, with the range in parentheses.
  3. c) Noncervical primary tumors with positive supraclavicular lymph nodes were defined as M1a.