|
Features
|
Total
|
Oct-4 expression n(%)a
|
P
|
χ
2
|
|---|
| | |
Negative
|
Positive
| | |
|---|
|
Gender
| | | |
0.330
|
0.674
|
|
Male
|
82
|
42 (51.2)
|
40 (48.8)
| | |
|
Female
|
31
|
14 (45.2)
|
17 (54.8)
| | |
|
Age (yr)b
| | | |
0.348
|
1.082
|
|
≤58
|
54
|
24 (44.4)
|
30 (55.6)
| | |
|
> 58
|
59
|
32 (54.2)
|
27 (45.8)
| | |
|
Smoking
| | | |
0.849
|
0.072
|
|
Yes
|
45
|
23 (51.1)
|
22 (48.9)
| | |
|
No
|
68
|
33 (48.5)
|
35 (51.5)
| | |
|
Histological type
| | | |
< 0.001
|
13.637
|
|
Adenocarcinoma
|
58
|
21 (36.2)
|
37 (63.8)
| | |
|
Squamous cell carcinoma
|
52
|
35 (67.3)
|
17 (32.7)
| | |
|
Large cell carcinoma
|
3
|
0 (0.0)
|
3 (100.0)
| | |
|
Histological differentiation
| | | |
0.001
|
32.463
|
|
Well differentiatedc
|
27
|
24 (88.9)
|
3 (11.1)
| | |
|
Moderately differentiated
|
34
|
20 (58.8)
|
14 (41.2)
| | |
|
Poorly differentiatedd
|
52
|
12 (23.1)
|
40 (76.9)
| | |
|
Adenocarcinoma
| | | |
0.001
|
17.324
|
|
Well differentiatedc
|
15
|
12 (80.0)
|
3 (20.0)
| | |
|
Moderately differentiated
|
14
|
4 (28.6)
|
10 (71.4)
| | |
|
Poorly differentiated
|
29
|
5 (17.2)
|
24 (82.8)
| | |
|
Squamous cell carcinoma
| | | |
0.001
|
16.780
|
|
Well differentiated
|
12
|
12 (100.0)
|
0 (0.0)
| | |
|
Moderately differentiated
|
20
|
16 (80.0)
|
4 (20.0)
| | |
|
Poorly differentiated
|
20
|
7 (35.0)
|
13 (65.0)
| | |
|
Local advance
| | | |
0.205
|
3.172
|
|
T1
|
30
|
17 (56.7)
|
13 (43.3)
| | |
|
T2
|
48
|
26 (54.2)
|
22 (45.8)
| | |
|
T3/T4
|
35
|
13 (37.1)
|
22 (62.9)
| | |
|
Lymph node metastasis
| | | |
0.466
|
1.529
|
|
N0
|
46
|
22 (47.8)
|
24 (52.2)
| | |
|
N1
|
23
|
14 (60.9)
|
9 (39.1)
| | |
|
N2
|
44
|
20 (45.5)
|
24 (54.5)
| | |
|
Clinical stage
| | | |
0.680
|
0.227
|
|
I/II
|
81
|
39 (48.1)
|
42 (51.9)
| | |
|
III/IV
|
32
|
17 (53.1)
|
15 (46.9)
| | |
|
MVD expressiona
| | | |
0.348
|
1.082
|
|
Positive
|
59
|
32 (54.2)
|
27 (45.8)
| | |
|
Negative
|
54
|
24 (44.4)
|
30 (55.6)
| | |
|
VEGF expressiona
| | | |
0.574
|
0.435
|
|
Positive
|
57
|
30 (52.6)
|
27 (47.4)
| | |
|
Negative
|
56
|
26 (46.4)
|
30 (53.6)
| | |
|
Ki-67 expressiona
| | | |
0.001
|
16.430
|
|
Positive
|
54
|
16 (29.6)
|
38 (70.4)
| | |
|
Negative
|
59
|
40 (67.8)
|
19 (32.2)
| | |
- aPatients were divided according to the median values of immunohistochemical histoscores
- bPatients were divided according to median age
- cBronchioloalveolar carcinoma was included in well differentiated
- dLarge cell carcinoma was included in poorly differentiated
