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Table 1 Association of Oct-4 Expression with clinical features in NSCLC

From: Clinicopathological significance of non-small cell lung cancer with high prevalence of Oct-4 tumor cells

Features Total Oct-4 expression n(%)a P χ 2
   Negative Positive   
Gender     0.330 0.674
   Male 82 42 (51.2) 40 (48.8)   
   Female 31 14 (45.2) 17 (54.8)   
Age (yr)b     0.348 1.082
   ≤58 54 24 (44.4) 30 (55.6)   
   > 58 59 32 (54.2) 27 (45.8)   
Smoking     0.849 0.072
   Yes 45 23 (51.1) 22 (48.9)   
   No 68 33 (48.5) 35 (51.5)   
Histological type     < 0.001 13.637
   Adenocarcinoma 58 21 (36.2) 37 (63.8)   
   Squamous cell carcinoma 52 35 (67.3) 17 (32.7)   
   Large cell carcinoma 3 0 (0.0) 3 (100.0)   
Histological differentiation     0.001 32.463
   Well differentiatedc 27 24 (88.9) 3 (11.1)   
   Moderately differentiated 34 20 (58.8) 14 (41.2)   
   Poorly differentiatedd 52 12 (23.1) 40 (76.9)   
Adenocarcinoma     0.001 17.324
   Well differentiatedc 15 12 (80.0) 3 (20.0)   
   Moderately differentiated 14 4 (28.6) 10 (71.4)   
   Poorly differentiated 29 5 (17.2) 24 (82.8)   
Squamous cell carcinoma     0.001 16.780
   Well differentiated 12 12 (100.0) 0 (0.0)   
   Moderately differentiated 20 16 (80.0) 4 (20.0)   
   Poorly differentiated 20 7 (35.0) 13 (65.0)   
Local advance     0.205 3.172
   T1 30 17 (56.7) 13 (43.3)   
   T2 48 26 (54.2) 22 (45.8)   
   T3/T4 35 13 (37.1) 22 (62.9)   
Lymph node metastasis     0.466 1.529
   N0 46 22 (47.8) 24 (52.2)   
   N1 23 14 (60.9) 9 (39.1)   
   N2 44 20 (45.5) 24 (54.5)   
Clinical stage     0.680 0.227
   I/II 81 39 (48.1) 42 (51.9)   
   III/IV 32 17 (53.1) 15 (46.9)   
MVD expressiona     0.348 1.082
   Positive 59 32 (54.2) 27 (45.8)   
   Negative 54 24 (44.4) 30 (55.6)   
VEGF expressiona     0.574 0.435
   Positive 57 30 (52.6) 27 (47.4)   
   Negative 56 26 (46.4) 30 (53.6)   
Ki-67 expressiona     0.001 16.430
   Positive 54 16 (29.6) 38 (70.4)   
   Negative 59 40 (67.8) 19 (32.2)   
  1. aPatients were divided according to the median values of immunohistochemical histoscores
  2. bPatients were divided according to median age
  3. cBronchioloalveolar carcinoma was included in well differentiated
  4. dLarge cell carcinoma was included in poorly differentiated