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Table 1 Patient characteristics at diagnosis

From: IgD multiple myeloma a descriptive report of 17 cases: survival and response to therapy

 

Number of patients = 17

Male/Female

11/6

Median Age at diagnosis yr (range)

55 (37-78) years

 

≤ 65 y = 13 (76.5%), ≥ 65 y = 4 (23.5%)

ISS stage at diagnosis

 

I

7

II

2

III

5

Unknown

3

Performance status

 

ECOG < 2

9

ECOG > 2

8

Light chain type

 

k

6

λ

11

Bone marrow infiltration

30% (10-70%)

Extra osseous disease

0

Bone lesions

14/17 (82%)

Median serum monoclonal protein g/dl

1.05 (0.09-5)

Median Urine monoclonal protein g/24 h

0.79 (0-28)

Urine immunofixation positive

12/17 (70%)

Serum β2 microglobulin > 5.5 mg/L

5/17 (29%)

Serum albumin < 3.5 g/dl

5/17 (29%)

eGFR < 50 ml/min

8/17 (47%)

Serum Calcium > 12 mg/dl

1/17

Amyloidosis

1/17

Hemoglobin g/dl, median (range)

11.9 (6.5-15)

< 10

5/17 (29%)

WBC count 109/L, median (range)

6.57 (3.19-16.8)

> 7 × 109/L

7/17 (41%)

Platelet count 109/L, median (range)

214 (74-518)

< 100 × 109/L

1/17