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Table 1 Relationship between AM expression and clinicopathological features in EOCs

From: Adrenomedullin expression in epithelial ovarian cancers and promotes HO8910 cell migration associated with upregulating integrin α5β1 and phosphorylating FAK and paxillin

Clinicopathological features

n

AM expression

  

-

+

++

+++

P value

Age(years)

     

0.705

< 55

56

5

18

12

21

 

≥ 55

40

3

9

9

19

 

Histotype

     

0.155

Serous

75

7

17

17

34

 

Non serous

21

1

10

4

6

 

Residual tumor after initial laparotomy

     

0.000*

< 1 cm

42

1

21

10

10

 

≥ 1 cm

53

7

6

11

29

 

Undetermined

1

0

0

0

1

 

Differentiation

     

0.199

Well-differentiated

27

4

11

6

6

 

Moderately-differentiated

23

1

8

3

11

 

Poorly-differentiated

39

3

7

11

18

 

Undetermined

7

0

1

1

5

 

FIGO staging

     

0.003*

I

17

1

10

1

5

 

II

19

0

10

4

5

 

III

53

6

7

13

27

 

IV

7

1

0

3

3

 

Serum CA125

     

0.301

≥ 500

52

5

11

13

23

 

< 500

41

3

16

7

15

 

Undetermined

3

0

0

1

2

 
  1. *P < 0.05
  2. EOC = epithelial ovarian cancer; AM = Adrenomedullin; FIGO = International Federation of Gynecology and Obstetrics