Table 3 Univariate analysis of Clinicopathological features, tumor markers, and patient survival

Gender (Male vs. Female)

1.370 (0.744-2.524)

0.313

1.341 (0.713-2.421)

0.381

Age (≤ 60 vs.>60)

1.433 (0.789-2.604)

0.237

1.450 (0.798-2.635)

0.223

Nationality (The Han vs. The Zhuang)

0.929 (0.480-1.800)

0.827

0.964 (0.497-1.867)

0.912

Histology (Squamous carcinoma vs. Adenocarcinoma)

0.541 (0.267-1.095)

0.088

0.559 (0.276-1.133)

0.106

Differentiation (Well and moderate vs. Poor)

0.992 (0.528-1.866)

0.980

0.953 (0.506-1.795)

0.881

Metastasis lymphatics (Yes vs. No)

0.429 (0.236-0.780)

0.006**

0.435 (0.238-0.793)

0.007**

TNM stage (I+II vs. III+IV)

2.267 (1.257-4.090)

0.007**

2.217 (1.227-4.003)

0.008**

ERCC1 (positive vs. negative)

0.326 (0.165-0.645)

0.001**

0.333 (0.169-0.660)

0.002**

BAG-1 (positive vs. negative)

0.367 (0.202-0.665)

0.001**

0.363 (0.200-0.658)

0.001**

BRCA1 (positive vs. negative)

0.546 (0.270-1.105)

0.093

0.505 (0.250-1.021)

0.057

RRM1 (positive vs. negative)

0.539 (0.314-1.143)

0.120

0.590 (0.309-1.126)

0.110

TUBB3 (positive vs. negative)

0.665 (0.319-1.383)

0.275

0.701 (0.338-1.458)

0.342