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Table 3 Univariate analysis of Clinicopathological features, tumor markers, and patient survival

From: Combined analysis of mRNA expression of ERCC1, BAG-1, BRCA1, RRM1 and TUBB3 to predict prognosis in patients with non-small cell lung cancer who received adjuvant chemotherapy

Variable PFS HR (95% CI) P value OS HR (95% CI) P value
Gender (Male vs. Female) 1.370 (0.744-2.524) 0.313 1.341 (0.713-2.421) 0.381
Age (≤ 60 vs.>60) 1.433 (0.789-2.604) 0.237 1.450 (0.798-2.635) 0.223
Nationality (The Han vs. The Zhuang) 0.929 (0.480-1.800) 0.827 0.964 (0.497-1.867) 0.912
Histology (Squamous carcinoma vs. Adenocarcinoma) 0.541 (0.267-1.095) 0.088 0.559 (0.276-1.133) 0.106
Differentiation (Well and moderate vs. Poor) 0.992 (0.528-1.866) 0.980 0.953 (0.506-1.795) 0.881
Metastasis lymphatics (Yes vs. No) 0.429 (0.236-0.780) 0.006** 0.435 (0.238-0.793) 0.007**
TNM stage (I+II vs. III+IV) 2.267 (1.257-4.090) 0.007** 2.217 (1.227-4.003) 0.008**
ERCC1 (positive vs. negative) 0.326 (0.165-0.645) 0.001** 0.333 (0.169-0.660) 0.002**
BAG-1 (positive vs. negative) 0.367 (0.202-0.665) 0.001** 0.363 (0.200-0.658) 0.001**
BRCA1 (positive vs. negative) 0.546 (0.270-1.105) 0.093 0.505 (0.250-1.021) 0.057
RRM1 (positive vs. negative) 0.539 (0.314-1.143) 0.120 0.590 (0.309-1.126) 0.110
TUBB3 (positive vs. negative) 0.665 (0.319-1.383) 0.275 0.701 (0.338-1.458) 0.342
  1. ** represent P < 0.01