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Figure 2 | Journal of Experimental & Clinical Cancer Research

Figure 2

From: Inhibition of dendritic cell migration by transforming growth factor-β1 increases tumor-draining lymph node metastasis

Figure 2

Concentrations of TGF-β1 in tumor draining lymph nodes. A, TGF-β1 levels in tumor-draining lymph nodes (TDLNs) and the contralateral nodes (non-TDNLs) in the same mice were assessed using an ELISA. Prior to inoculation, tumor cells were transfected with either TGF-β1 gene or empty vector (mock). Note that in mice inoculated with TGF-β1-transfectants, TGF-β1 levels were higher in TDLNs than non-TDNLs. TGF-β1 levels were also higher in TDLNs draining TGF-β1-expressing tumors than tumors not expressing TGF-β1. B, Serum TGF-β1 levels measured in the same mice as in panel A. Serum TGF-β1 levels did not differ among the groups. *P < 0.05. n = 5 in each group.

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