Motility of PC-3 and LNCaP cells upon stimulation of adipose tissue-derived CM from explants and SVF. Data represent mean ± SE of at least 20 representative cell trajectories per each tested condition, from four distinct subjects. Bars represent mean speed (MS) per gram of adipose tissue and plots the logarithmically transformed final relative distance to origin per gram of adipose tissue (FRDO). A. FRDO and MS of PC-3 cells (* P < 0.05 and *** P < 0.0001 between treatment conditions). B. FRDO and MS of LNCaP cells (** P < 0.01 and *** P < 0.0001 between conditions). Analyses on MS were performed with Mann Whitney test, whereas FRDO was analyzed using independent samples t-test.SVF, stromal-vascular fraction; PP, periprostatic; VIS, visceral.