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Table 2 Correlation between cancer biomarkers and bone metastasis

From: Establishment of a biomarker model for predicting bone metastasis in resected stage III non-small cell lung cancer

Biomarkers Bone metastasis n (%) Non-bone metastasis n (%) P value
OPN + 40 (93.0) 48 (77.4) 0.033
  - 3 (7.0) 14 (22.6)  
c-Src + 45 (100) 56 (93.3) 0.133
  - 0 (0) 4 (6.7)  
MMP2 + 38 (88.4) 47 (75.8) 0.107
  - 5 (11.6) 15 (24.2)  
CXCR4 + 40 (90.9) 32 (52.5) 0.000
  - 4 (9.1) 29 (47.5)  
BSP + 44 (97.8) 49 (81.7) 0.012
  - 1 (2.2) 11 (18.3)  
PTHrP + 42 (68.8) 28 (63.4) 0.647
  - 19 (31.2) 16 (36.6)  
IGF-1R + 58 (95.1) 39 (88.6) 0.383
  - 3 (4.9) 5 (21.4)  
BMP4 + 22 (48.9) 51 (85) 0.000
  - 23 (51.1) 9 (15.0)  
PI3K + 43 (95.6) 55 (91.7) 0.696
  - 2 (4.4) 5 (8.3)  
NFκB + 58 (95.1) 39 (88.6) 0.383
  - 3 (4.9) 5 (21.4)