TY - JOUR AU - Herbst, R. S. AU - Heymach, J. V. AU - Lippman, S. M. PY - 2008 DA - 2008// TI - Lung cancer JO - N Engl J Med VL - 359 UR - https://doi.org/10.1056/NEJMra0802714 DO - 10.1056/NEJMra0802714 ID - Herbst2008 ER - TY - JOUR AU - Jemal, A. AU - Siegel, R. AU - Ward, E. AU - Hao, Y. AU - Xu, J. AU - Thun, M. J. PY - 2009 DA - 2009// TI - Cancer statistics, 2009 JO - CA Cancer J Clin VL - 59 UR - https://doi.org/10.3322/caac.20006 DO - 10.3322/caac.20006 ID - Jemal2009 ER - TY - JOUR AU - Boffetta, P. PY - 2004 DA - 2004// TI - Epidemiology of environmental and occupational cancer JO - Oncogene VL - 23 UR - https://doi.org/10.1038/sj.onc.1207715 DO - 10.1038/sj.onc.1207715 ID - Boffetta2004 ER - TY - JOUR AU - Patel, J. D. PY - 2005 DA - 2005// TI - Lung cancer in women JO - J Clin Oncol VL - 23 UR - https://doi.org/10.1200/JCO.2005.11.486 DO - 10.1200/JCO.2005.11.486 ID - Patel2005 ER - TY - JOUR AU - Subramanian, J. AU - Govindan, R. PY - 2007 DA - 2007// TI - Lung cancer in never smokers: a review JO - J Clin Oncol VL - 25 UR - https://doi.org/10.1200/JCO.2006.06.8015 DO - 10.1200/JCO.2006.06.8015 ID - Subramanian2007 ER - TY - JOUR AU - Samet, J. M. AU - Avila-Tang, E. AU - Boffetta, P. AU - Hannan, L. M. AU - Olivo-Marston, S. AU - Thun, M. J. PY - 2009 DA - 2009// TI - Lung cancer in never smokers: clinical epidemiology and environmental risk factors JO - Clin Cancer Res VL - 15 UR - https://doi.org/10.1158/1078-0432.CCR-09-0376 DO - 10.1158/1078-0432.CCR-09-0376 ID - Samet2009 ER - TY - JOUR AU - Paggi, M. G. AU - Vona, R. AU - Abbruzzese, C. AU - Malorni, W. PY - 2010 DA - 2010// TI - Gender-related disparities in non-small cell lung cancer JO - Cancer Lett VL - 298 UR - https://doi.org/10.1016/j.canlet.2010.08.009 DO - 10.1016/j.canlet.2010.08.009 ID - Paggi2010 ER - TY - JOUR AU - Miller, V. A. AU - Kris, M. G. AU - Shah, N. AU - Patel, J. AU - Azzoli, C. AU - Gomez, J. PY - 2004 DA - 2004// TI - Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer JO - J Clin Oncol VL - 22 UR - https://doi.org/10.1200/JCO.2004.08.158 DO - 10.1200/JCO.2004.08.158 ID - Miller2004 ER - TY - JOUR AU - Schlessinger, J. PY - 2002 DA - 2002// TI - Ligand-induced, receptor-mediated dimerization and activation of EGF receptor JO - Cell VL - 110 UR - https://doi.org/10.1016/S0092-8674(02)00966-2 DO - 10.1016/S0092-8674(02)00966-2 ID - Schlessinger2002 ER - TY - JOUR AU - Pollak, M. PY - 2008 DA - 2008// TI - Insulin and insulin-like growth factor signalling in neoplasia JO - Nat Rev Cancer VL - 8 UR - https://doi.org/10.1038/nrc2536 DO - 10.1038/nrc2536 ID - Pollak2008 ER - TY - JOUR AU - Mattarocci, S. AU - Abbruzzese, C. AU - Mileo, A. M. AU - Visca, P. AU - Antoniani, B. AU - Alessandrini, G. PY - 2009 DA - 2009// TI - Intracellular presence of insulin and its phosphorylated receptor in non-small cell lung cancer JO - J Cell Physiol VL - 221 UR - https://doi.org/10.1002/jcp.21916 DO - 10.1002/jcp.21916 ID - Mattarocci2009 ER - TY - JOUR AU - Bellacosa, A. AU - Kumar, C. C. AU - Di Cristofano, A. AU - Testa, J. R. PY - 2005 DA - 2005// TI - Activation of AKT kinases in cancer: implications for therapeutic targeting JO - Adv Cancer Res VL - 94 UR - https://doi.org/10.1016/S0065-230X(05)94002-5 DO - 10.1016/S0065-230X(05)94002-5 ID - Bellacosa2005 ER - TY - JOUR AU - Ruggero, D. AU - Sonenberg, N. PY - 2005 DA - 2005// TI - The Akt of translational control JO - Oncogene VL - 24 UR - https://doi.org/10.1038/sj.onc.1209098 DO - 10.1038/sj.onc.1209098 ID - Ruggero2005 ER - TY - JOUR AU - Testa, J. R. AU - Tsichlis, P. N. PY - 2005 DA - 2005// TI - AKT signaling in normal and malignant cells JO - Oncogene VL - 24 UR - https://doi.org/10.1038/sj.onc.1209100 DO - 10.1038/sj.onc.1209100 ID - Testa2005 ER - TY - JOUR AU - Bruhn, M. A. AU - Pearson, R. B. AU - Hannan, R. D. AU - Sheppard, K. E. PY - 2010 DA - 2010// TI - Second AKT: the rise of SGK in cancer signalling JO - Growth Factors VL - 28 UR - https://doi.org/10.3109/08977194.2010.518616 DO - 10.3109/08977194.2010.518616 ID - Bruhn2010 ER - TY - JOUR AU - Lang, F. AU - Bohmer, C. AU - Palmada, M. AU - Seebohm, G. AU - Strutz-Seebohm, N. AU - Vallon, V. PY - 2006 DA - 2006// TI - (Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms JO - Physiol Rev VL - 86 UR - https://doi.org/10.1152/physrev.00050.2005 DO - 10.1152/physrev.00050.2005 ID - Lang2006 ER - TY - JOUR AU - Liu, D. AU - Yang, X. AU - Songyang, Z. PY - 2000 DA - 2000// TI - Identification of CISK, a new member of the SGK kinase family that promotes IL-3-dependent survival JO - Curr Biol VL - 10 UR - https://doi.org/10.1016/S0960-9822(00)00733-8 DO - 10.1016/S0960-9822(00)00733-8 ID - Liu2000 ER - TY - JOUR AU - Mikosz, C. A. AU - Brickley, D. R. AU - Sharkey, M. S. AU - Moran, T. W. AU - Conzen, S. D. PY - 2001 DA - 2001// TI - Glucocorticoid receptor-mediated protection from apoptosis is associated with induction of the serine/threonine survival kinase gene, sgk-1 JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M010842200 DO - 10.1074/jbc.M010842200 ID - Mikosz2001 ER - TY - JOUR AU - Tangir, J. AU - Bonafe, N. AU - Gilmore-Hebert, M. AU - Henegariu, O. AU - Chambers, S. K. PY - 2004 DA - 2004// TI - SGK1, a potential regulator of c-fms related breast cancer aggressiveness JO - Clin Exp Metastasis VL - 21 UR - https://doi.org/10.1007/s10585-004-4226-8 DO - 10.1007/s10585-004-4226-8 ID - Tangir2004 ER - TY - JOUR AU - Failor, K. L. AU - Desyatnikov, Y. AU - Finger, L. A. AU - Firestone, G. L. PY - 2007 DA - 2007// TI - Glucocorticoid-induced degradation of glycogen synthase kinase-3 protein is triggered by serum- and glucocorticoid-induced protein kinase and Akt signaling and controls beta-catenin dynamics and tight junction formation in mammary epithelial tumor cells JO - Mol Endocrinol VL - 21 UR - https://doi.org/10.1210/me.2007-0143 DO - 10.1210/me.2007-0143 ID - Failor2007 ER - TY - JOUR AU - Cronin, M. AU - Pho, M. AU - Dutta, D. AU - Stephans, J. C. AU - Shak, S. AU - Kiefer, M. C. PY - 2004 DA - 2004// TI - Measurement of gene expression in archival paraffin-embedded tissues: development and performance of a 92-gene reverse transcriptase-polymerase chain reaction assay JO - Am J Pathol VL - 164 UR - https://doi.org/10.1016/S0002-9440(10)63093-3 DO - 10.1016/S0002-9440(10)63093-3 ID - Cronin2004 ER - TY - JOUR AU - Antonov, J. AU - Goldstein, D. R. AU - Oberli, A. AU - Baltzer, A. AU - Pirotta, M. AU - Fleischmann, A. PY - 2005 DA - 2005// TI - Reliable gene expression measurements from degraded RNA by quantitative real-time PCR depend on short amplicons and a proper normalization JO - Lab Invest VL - 85 UR - https://doi.org/10.1038/labinvest.3700303 DO - 10.1038/labinvest.3700303 ID - Antonov2005 ER - TY - JOUR AU - Bianchi, F. AU - Nicassio, F. AU - Di Fiore, P. P. PY - 2008 DA - 2008// TI - Unbiased vs. biased approaches to the identification of cancer signatures: the case of lung cancer JO - Cell Cycle VL - 7 UR - https://doi.org/10.4161/cc.7.6.5591 DO - 10.4161/cc.7.6.5591 ID - Bianchi2008 ER - TY - JOUR AU - Guan, P. AU - Huang, D. AU - He, M. AU - Zhou, B. PY - 2009 DA - 2009// TI - Lung cancer gene expression database analysis incorporating prior knowledge with support vector machine-based classification method JO - J Exp Clin Cancer Res VL - 28 UR - https://doi.org/10.1186/1756-9966-28-103 DO - 10.1186/1756-9966-28-103 ID - Guan2009 ER - TY - JOUR AU - Nakashima, R. A. AU - Paggi, M. G. AU - Pedersen, P. L. PY - 1984 DA - 1984// TI - Contributions of glycolysis and oxydative phosphorylation to adenosine-5'-triphosphate production in AS-30D hepatoma cells JO - Cancer Res VL - 44 ID - Nakashima1984 ER - TY - CHAP AU - Nakashima, R. A. AU - Paggi, M. G. AU - Arora, K. K. AU - Pedersen, P. L. ED - Lemasters, J. J. ED - Hackenbrock, C. R. ED - Thurman, R. G. ED - Westhoff, H. V. PY - 1990 DA - 1990// TI - Integration of mitochondrial function with high aerobic glycolysis in tumors: role of hexokinase binding to the outer mitochondrial membrane BT - Integration of Mitochondrial Function PB - Plenum Publishing Company CY - New York, N.Y. ID - Nakashima1990 ER - TY - JOUR AU - Wallace, D. C. PY - 2005 DA - 2005// TI - Mitochondria and cancer: Warburg addressed JO - Cold Spring Harb Symp Quant Biol VL - 70 UR - https://doi.org/10.1101/sqb.2005.70.035 DO - 10.1101/sqb.2005.70.035 ID - Wallace2005 ER - TY - JOUR AU - Pedersen, P. L. PY - 2007 DA - 2007// TI - Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen JO - J Bioenerg Biomembr VL - 39 UR - https://doi.org/10.1007/s10863-007-9094-x DO - 10.1007/s10863-007-9094-x ID - Pedersen2007 ER - TY - JOUR AU - Brickley, D. R. AU - Mikosz, C. A. AU - Hagan, C. R. AU - Conzen, S. D. PY - 2002 DA - 2002// TI - Ubiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1) JO - J Biol Chem VL - 277 UR - https://doi.org/10.1074/jbc.M207604200 DO - 10.1074/jbc.M207604200 ID - Brickley2002 ER - TY - JOUR AU - Mattmann, M. E. AU - Stoops, S. L. AU - Lindsley, C. W. PY - 2011 DA - 2011// TI - Inhibition of Akt with small molecules and biologics: historical perspective and current status of the patent landscape JO - Expert Opin Ther Pat VL - 21 UR - https://doi.org/10.1517/13543776.2011.587959 DO - 10.1517/13543776.2011.587959 ID - Mattmann2011 ER - TY - JOUR AU - Morrow, J. K. AU - Du-Cuny, L. AU - Chen, L. AU - Meuillet, E. J. AU - Mash, E. A. AU - Powis, G. PY - 2011 DA - 2011// TI - Recent development of anticancer therapeutics targeting Akt JO - Recent Pat Anticancer Drug Discov VL - 6 UR - https://doi.org/10.2174/157489211793980079 DO - 10.2174/157489211793980079 ID - Morrow2011 ER - TY - JOUR AU - Hixon, M. L. AU - Paccagnella, L. AU - Millham, R. AU - Perez-Olle, R. AU - Gualberto, A. PY - 2010 DA - 2010// TI - Development of inhibitors of the IGF-IR/PI3K/Akt/mTOR pathway JO - Rev Recent Clin Trials VL - 5 UR - https://doi.org/10.2174/157488710792007329 DO - 10.2174/157488710792007329 ID - Hixon2010 ER -