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Table 2 Evaluation of SGK1 (all variants) mRNA expression in NSCLC samples by qPCR: correlation with clinico-pathological parameters.

From: Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas

   Null/low SGK1 expression n = 22 Medium SGK1 expression n = 22 High SGK1 expression n = 22 P-value
   Patient age (years)§ 69.1 ± 1.6 66.3 ± 2.4 65.2 ± 1.8 0.386 (NS)
Gender Male 11 13 15 0.471 (NS)
  Female 11 9 7  
Smoking habit Smokers 10 12 11 0.834 (NS)
  Non-smokers 12 10 11  
Histopathological Subtype Adenocarcinoma 15 12 8 0.022
  Squamous cell carcinoma 3 10 12  
  Other 4 0 2  
Histopathological Grade G1 5 0 1 0.026
  G2 8 15 9  
  G3 9 7 12  
Tumor Size T 1 9 2 6 0.013
  T 2 12 15 10  
  T 3 1 2 6  
  T 4 0 3 0  
Lymph Node Stage N 0 18 14 16 0.315 (NS)
  N 1 0 4 2  
  N 2 3 3 4  
  N/A 1 1 0  
Tumor Stage Stage I a 10 2 5 0.028
  Stage I b 7 10 6  
  Stage II a 1 0 0  
  Stage II b 1 2 6  
  Stage III a 3 4 5  
  Stage III b 0 3 0  
  1. § Average values; in bold and underlined = statistically significant results; N.S. = non-significant.