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Table 2 Evaluation of SGK1 (all variants) mRNA expression in NSCLC samples by qPCR: correlation with clinico-pathological parameters.

From: Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas

  

Null/low SGK1 expression

n = 22

Medium SGK1 expression

n = 22

High SGK1 expression

n = 22

P-value

   Patient age (years)§

69.1 ± 1.6

66.3 ± 2.4

65.2 ± 1.8

0.386 (NS)

Gender

Male

11

13

15

0.471 (NS)

 

Female

11

9

7

 

Smoking habit

Smokers

10

12

11

0.834 (NS)

 

Non-smokers

12

10

11

 

Histopathological Subtype

Adenocarcinoma

15

12

8

0.022

 

Squamous cell carcinoma

3

10

12

 
 

Other

4

0

2

 

Histopathological Grade

G1

5

0

1

0.026

 

G2

8

15

9

 
 

G3

9

7

12

 

Tumor Size

T 1

9

2

6

0.013

 

T 2

12

15

10

 
 

T 3

1

2

6

 
 

T 4

0

3

0

 

Lymph Node Stage

N 0

18

14

16

0.315 (NS)

 

N 1

0

4

2

 
 

N 2

3

3

4

 
 

N/A

1

1

0

 

Tumor Stage

Stage I a

10

2

5

0.028

 

Stage I b

7

10

6

 
 

Stage II a

1

0

0

 
 

Stage II b

1

2

6

 
 

Stage III a

3

4

5

 
 

Stage III b

0

3

0

 
  1. § Average values; in bold and underlined = statistically significant results; N.S. = non-significant.