Figure 2

In vivo efficacy of sigma-2 receptor ligands. Athymic nude mice inoculated subcutaneously with 1x106 Bxpc3 cells were treated daily with sigma-2 receptor ligands SV119, SW43, PB28, or PB282 when tumors reached an average of 5 mm in diameter. Data represents mean ± SEM, n = 7–10 per group, * p < 0.05.