Figure 1
Proliferation of CA46 cells in the absence and presence of baicalin. Cells were seeded at a density of 1 × 104/well and treated with baicalin at the concentrations and for the times indicated. Cytotoxicity was determined according to the MTT assay. Sampling was performed in triplicate for each experimental condition, and findings are expressed as means ± standard deviation for three independent experiments. (A) Proliferation as a function of incubation time and baicalin concentration. Absorbance maxima are provided on the ordinate. (B) Rates of proliferation as a function of baicalin concentration. Cells were treated for 48 h with baicalin at the concentrations indicated. Proliferation rates were determined as described in Materials and methods. *P <0.01 compared to the solvent control; †P <0.01 compared to 5 μM baicalin; ‡P <0.01 compared to 10 μM baicalin.