Downregulation of gastrokine-1 in gastric cancer tissues and restoration of its expression induced gastric cancer cells to apoptosis

Table 2 GKN1 expression detected by immunohistochemistry in gastric tissues

Histological type	Number of patient	-	+	++	+++	P value¹
Normal gastric mucosa	20	0	0	0	20	< 0.05
Atrophic gastritis	40	0	15	20	5
Intestinal metaplasia	40	21	19	0	0
Dysplastic lesion	40	26	14	0	0
Gastric cancer	39	34	5	0	0

¹Comparison between healthy volunteers, atrophic gastritis, intestinal metaplasia, dysplasia and gastric cancer tissues, P < 0.05.

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