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Table 3 5-FU induction of apoptosis in gastric cancer AGS cells

From: Downregulation of gastrokine-1 in gastric cancer tissues and restoration of its expression induced gastric cancer cells to apoptosis

Group

Time (h)

5-FU-induced apoptosis (%)

  

0.25 mmol/L

0.5 mmol/L

1.0 mmol/L

Vector transfected

24

5.53 ± 0.06

7.70 ± 0.10

9.57 ± 0.21

GKN1 transfected

24

13.03 ± 0.40

14.93 ± 0.15

19.73 ± 0.23

Vector transfected

48

8.23 ± 0.21

12.33 ± 0.21

14.33 ± 0.06

GKN1 transfected

48

18.13 ± 0.72

23.30 ± 0.79

34.83 ± 0.67