Figure 2
From: Oncolytic adenovirus armed with IL-24 Inhibits the growth of breast cancer in vitro and in vivo
CNHK600-IL24 selectively produced IL-24 and induced cell death in a breast cancer cell line. (A) Selective replication of CNHK600-IL24 in MDA-MB-231 cells. MRC-5 or MDA-MB-231 cells were infected with CNHK600-IL24 at a MOI of 5 and virus titers from the supernatant were measured by the TCID50 method at indicated time points. (B) Five days after infection with CNHK600-IL24 or CNHK600-EGFP at the indicated range of MOI, the viability of MDA-MB-231 and MRC-5 was measured by MTT assay.