Figure 4From: Over-expression of BMPR-IB reduces the malignancy of glioblastoma cells by upregulation of p21 and p27Kip1Induction of differentiation by BMPR-IB in human glioma cell lines. (A) After infection and transfection with rAAV-BMPR-IB and si-BMPR-IB, the expression of GFAP of glioblastoma cells was detected by immunofluorescence (left), and the morphological alterations were examined by phase contrast microscope(right). (B) WB analysis showed that BMPR-IB infection induced the expression of endogenous GFAP and inhibited the expression of Nestin, whereas BMPR-IB knock-down decreased the expression of GFAP and increased the expression of Nestin.Back to article page