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Table 5 Deregulated miRNAs ( n= 19) consistently reported in profiling studies (lung SCC tissue versus normal)

From: Meta-analysis of human lung cancer microRNA expression profiling studies comparing cancer tissues with normal tissues

Direction of expression miRNA namea No. of studies with same direction (reference) Total number of tissue samples tested Subset of studies with fold change
     No. of studies Total number of tissue samples tested Mean fold change Range
Up-regulated miR-210 4 (24,26,29,30) 247 1 30 2.37 -
  miR-203 3 (24,26,30) 217 0 - - -
  miR-205 3 (26,29,30) 176 1 30 2.99 -
  miR-21 3 (29,30,33) 116 2 38 2.53 1.74 - 3.31
  miR-31 3 (26,29,33) 106 2 38 4.42 1.58 - 7.26
  miR-182 2 (24,26) 139 0 - - -
  miR-200c 2 (24,29) 101 1 30 1.66 -
  miR-18a 2 (26,33) 76 1 8 2.24 -
Down-regulated miR-126 4 (26,29,31,33) 112 3 44 0.18 0.00 - 0.42
  miR-30a 4 (26,29,31,33) 112 3 44 0.28 0.11 - 0.53
  miR-30d 3 (29,31,33) 44 3 44 0.33 0.22 - 0.54
  miR-195 2 (26,29) 98 1 30 0.53 -
  miR-497 2 (26,29) 98 1 30 0.66 -
  miR-126* 2 (30,33) 86 1 8 0.16 -
  miR-143 2 (30,33) 86 1 8 0.24 -
  miR-145 2 (26,33) 76 1 8 0.48 -
  miR-451 2 (29,33) 38 2 38 0.37 0.22 - 0.53
  miR-30b 2 (29,33) 38 2 38 0.50 0.48 - 0.53
  miR-101 2 (31,33) 14 2 14 0.34 0.29 - 0.39
  1. a The asterisk is part of the miRNA nomenclature system and is not linked to any footnote specific to this table. SCC, squamous cell carcinoma.