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Table 6 Deregulated miRNAs ( n= 7) consistently reported in profiling studies (lung ADC tissue versus normal)

From: Meta-analysis of human lung cancer microRNA expression profiling studies comparing cancer tissues with normal tissues

Direction of expression miRNA name No. of studies with same direction (reference) Total number of tissue samples tested Subset of studies with fold change
     No. of studies Total number of tissue samples tested Mean fold change Range
Up-regulated miR-210 3 (22,30,32) 376 2 246 1.96 1.75 - 2.17
  miR-182 2 (22,32) 246 2 246 2.03 1.85 - 2.22
  miR-31 2 (22,32) 246 2 246 1.83 1.60 - 2.05
  miR-21 2 (30,32) 170 1 40 2.56 -
Down-regulated miR-218 2 (22,32) 246 2 246 0.61 0.60 - 0.62
  miR-145 2 (30,32) 170 1 40 0.38 -
  miR-126 2 (30,32) 170 1 40 0.46 -
  1. ADC, adenocarcinoma/adenosquamous carcinoma.