Table 6 Deregulated miRNAs ( n = 7) consistently reported in profiling studies (lung ADC tissue versus normal)
Direction of expression | miRNA name | No. of studies with same direction (reference) | Total number of tissue samples tested | Subset of studies with fold change | |||
|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | No. of studies | Total number of tissue samples tested | Mean fold change | Range |
Up-regulated | miR-210 | 3 (22,30,32) | 376 | 2 | 246 | 1.96 | 1.75 - 2.17 |
| Â | miR-182 | 2 (22,32) | 246 | 2 | 246 | 2.03 | 1.85 - 2.22 |
| Â | miR-31 | 2 (22,32) | 246 | 2 | 246 | 1.83 | 1.60 - 2.05 |
| Â | miR-21 | 2 (30,32) | 170 | 1 | 40 | 2.56 | - |
Down-regulated | miR-218 | 2 (22,32) | 246 | 2 | 246 | 0.61 | 0.60 - 0.62 |
| Â | miR-145 | 2 (30,32) | 170 | 1 | 40 | 0.38 | - |
| Â | miR-126 | 2 (30,32) | 170 | 1 | 40 | 0.46 | - |