Figure 7

Western blot analysis of to Stat3 expression in K5.Stat3C transgenic (TG) mouse epidermis. TPA (3.4 nmol) was administered twice a week for 2 wk and mice were euthanized at 48 h. Mice were co-treated with vehicle (acetone 200 μL), ACA (340 nmol), galanga extract (GE, corresponding to 340 nmol ACA) or FA (2.2 nmol). Figures represent densitometry analysis of ratio of Stat3/actin (panel A); and p-Tyr705Stat3/actin panel B (Means ± SE of 6–8 individual mice).