Figure 3
From: TGFBI promoter hypermethylation correlating with paclitaxel chemoresistance in ovarian cancer
MSP analysis of TGFBI in paplitaxel resistant cell lines after demethylation by 5-aza-dc. After 5-aza-dc treatment, a "U" band appeared while the "M" band did not disappear in A2780/TR cell line. In another cell line SKOV3/TR, the "M" band disappeared and only a "U" band was left. DL: Marker DL2000; SKOV3/TR, A2780/TR: before treatment; SKOV3/TR', A2780/TR': after treatment; U: unmethylation, M: methylation.