Figure 5From: 125I seed irradiation induces up-regulation of the genes associated with apoptosis and cell cycle arrest and inhibits growth of gastric cancer xenograftsEffects of 125I irradiation on gene methylation and mRNA expression in xenografts. (A) Relative expression of DNMT1 was detected using qRT-PCR. (B) Effects of 125I irradiation on gene methylation of BNIP3 and WNT9A in xenografts assayed by MeDIP-PCR. BNIP3 and WNT9A in treatment group displayed lower level of methylation when compared with control group. (C) Relative expression of BNIP3 and WNT9A was detected using qRT-PCR. Data are expressed as the mean ± SD of 6 samples. The significance of the varieties between the control group and 125I treatment group was analyzed through student’s t-t test. (☆: P < 0.05).Back to article page