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Table 2 The irradiation-induced genes with promoter hypermethylation in the non-irradiated tumors

From: 125I seed irradiation induces up-regulation of the genes associated with apoptosis and cell cycle arrest and inhibits growth of gastric cancer xenografts

GENE_NAME DESCRIPTION Fold change Regulation P-value FDR
DRD5 dopamine receptor D5 1.4 up 2.85E-04 0.03
PFN2 profilin 2 1.4 up 0.021 0.05
SKI v-ski sarcoma viral oncogene homolog (avian) 1.6 up 0.005 0.04
WNT9A wingless-type MMTV integration site family, member 9A 1.6 up 0.048 0.05
CXorf12 chromosome X open reading frame 12 2.0 up 0.012 0.05
BNIP3 BCL2/adenovirus E1B 19 kDa interacting protein 3 2.0 up 0.045 0.05
CHST10 carbohydrate sulfotransferase 10 2.2 up 0.010 0.05
PNMA1 paraneoplastic antigen MA1 1.3 up 0.001 0.04
C18orf55 chromosome 18 open reading frame 55 1.4 up 0.009 0.05
TRAK2 trafficking protein, kinesin binding 2 1.3 up 0.047 0.05
LRRC49 leucine rich repeat containing 49 1.5 up 0.041 0.05
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 1.4 up 0.027 0.05
USP31 ubiquitin specific peptidase 31 1.5 up 0.021 0.05
GSG2 germ cell associated 2 (haspin) 1.6 up 0.035 0.05
ATAD1 ATPase family, AAA domain containing 1 1.3 up 0.006 0.04
MGC16385 hypothetical protein MGC16385 1.4 up 0.046 0.05
TCEB3C transcription elongation factor B polypeptide 3 C (elongin A3) 2.0 up 0.006 0.04
LONRF1 LON peptidase N-terminal domain and ring finger 1 1.4 up 0.014 0.05
SAMD11 sterile alpha motif domain containing 11 1.4 up 0.031 0.05
SLC35E2 solute carrier family 35, member E2 1.3 up 0.027 0.05