Table 2 The irradiation-induced genes with promoter hypermethylation in the non-irradiated tumors
GENE_NAME | DESCRIPTION | Fold change | Regulation | P-value | FDR |
|---|---|---|---|---|---|
DRD5 | dopamine receptor D5 | 1.4 | up | 2.85E-04 | 0.03 |
PFN2 | profilin 2 | 1.4 | up | 0.021 | 0.05 |
SKI | v-ski sarcoma viral oncogene homolog (avian) | 1.6 | up | 0.005 | 0.04 |
WNT9A | wingless-type MMTV integration site family, member 9A | 1.6 | up | 0.048 | 0.05 |
CXorf12 | chromosome X open reading frame 12 | 2.0 | up | 0.012 | 0.05 |
BNIP3 | BCL2/adenovirus E1B 19 kDa interacting protein 3 | 2.0 | up | 0.045 | 0.05 |
CHST10 | carbohydrate sulfotransferase 10 | 2.2 | up | 0.010 | 0.05 |
PNMA1 | paraneoplastic antigen MA1 | 1.3 | up | 0.001 | 0.04 |
C18orf55 | chromosome 18 open reading frame 55 | 1.4 | up | 0.009 | 0.05 |
TRAK2 | trafficking protein, kinesin binding 2 | 1.3 | up | 0.047 | 0.05 |
LRRC49 | leucine rich repeat containing 49 | 1.5 | up | 0.041 | 0.05 |
EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 1.4 | up | 0.027 | 0.05 |
USP31 | ubiquitin specific peptidase 31 | 1.5 | up | 0.021 | 0.05 |
GSG2 | germ cell associated 2 (haspin) | 1.6 | up | 0.035 | 0.05 |
ATAD1 | ATPase family, AAA domain containing 1 | 1.3 | up | 0.006 | 0.04 |
MGC16385 | hypothetical protein MGC16385 | 1.4 | up | 0.046 | 0.05 |
TCEB3C | transcription elongation factor B polypeptide 3 C (elongin A3) | 2.0 | up | 0.006 | 0.04 |
LONRF1 | LON peptidase N-terminal domain and ring finger 1 | 1.4 | up | 0.014 | 0.05 |
SAMD11 | sterile alpha motif domain containing 11 | 1.4 | up | 0.031 | 0.05 |
SLC35E2 | solute carrier family 35, member E2 | 1.3 | up | 0.027 | 0.05 |