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Table 3 Association between EGFR mutation and EGFR phosphorylations

From: Phosphorylated EGFR expression may predict outcome of EGFR-TKIs therapy for the advanced NSCLC patients with wild-type EGFR

Variables (no.of patients, %) EGFR mutation pTyr1068 pTyr1173
   + - p + - p + - p
Total 92(44.9) 113(55.1)   164(80.0) 41(20.0)   95(57.6) 70(42.4)  
EGFR mutation +     84(91.3) 8(8.7) <0.001 41(54.7) 34(45.3) 0.297
  -     80(70.8) 33(29.2)   54(60.0) 36(40.0)  
pTyr1068 + 84(51.2) 80(48.8) <0.001     82(61.2) 52(38.8) 0.069
  - 8(19.5) 33(80.5)      13(41.9) 18(58.1)  
pTyr1173 + 41(43.2) 54(56.8) 0.297 82(86.3) 13(13.7) 0.069    
  - 34(48.6) 36(51.4)   52(74.3) 18(25.7)     
  1. Abbreviations: EGFR, epidermal growth factor receptor; pTyr, phophorylated tyrosine.