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Table 3 Top 15 of differentially expressed genes, between bad versus good outcome PDAC samples

From: Molecular markers associated with outcome and metastasis in human pancreatic cancer

Gene Symbol

Gene name

Fold bad/good

P-value

CPB1

Carboxypeptidase B1

31.03

3.16E-05

CTRB2

Chymotrypsinogen B2

24.38

2.78E-05

PLA2G1B

Phospholipase A2, group IB, pancreas

20.35

0.00022

PNLIPRP2

Pancreatic lipase-related protein 2

19.48

0.00019

PNLIP

Pancreatic lipase

19.06

0.00048

CEL

Carboxyl ester lipase (bile salt-stimulated lipase)

18.89

0.00011

CPA1

Carboxypeptidase A1, pancreatic

18.57

6.68E-05

CELA3A

Chymotrypsin-like elastase family, member 3A

17.10

2.47E-05

CELA3B

Chymotrypsin-like elastase family, member 3B

16.56

2.01E-05

CPA2

Carboxypeptidase A2 (pancreatic)

14.43

0.00016

CLPS

Colipase, pancreatic

11.55

0.00035

CTRC

Chymotrypsin C (caldecrin)

11.17

0.00023

KRT6A

Keratin 6A

10.23

0.00090

PRSS2

Protease, serine, 2 (trypsin 2)

8.87

0.00092

DEFA5

Defensin, alpha 5, Paneth cell-specific

−13.95

9.04E-08

SLC26A3

Solute carrier family 26, member 3

−13.76

4.08E-08

SI

Sucrase-isomaltase (alpha-glucosidase)

−8.95

2.29E-07

TAC3

Tachykinin 3

−8.06

0.00029

PRSS7

Protease, serine, 7 (enterokinase)

−6.93

1.99E-08

DEFA6

Defensin, alpha 6, Paneth cell-specific

−6.50

1.50E-06

VIP

Vasoactive intestinal polypeptide

−6.12

1.82E-05

RBP2

Retinol binding protein 2, cellula

−5.68

1.72E-07

UGT2B17

UDP glucuronosyltransferase 2 family, polypeptide B17

−5.33

0.00090

CDH19

Cadherin 19, type 2

−4.90

0.00089

SYNM

Synemin, intermediate filament protein

−4.86

1.53E-05

FOXA1

Forkhead box A1

−4.30

6.00E-07

CLCA1

Chloride channel accessory 1

−3.90

2.05E-05

ELF5

E74-like factor 5

−3.74

1.50E-06

AKR1C1

Aldo-keto reductase family 1, member C1

−3.63

0.00043