Journal of Experimental & Clinical Cancer Research

Table 4 Upregulated KEGG pathways (GENECODIS) in primary PDAC and metastatic PDAC samples

From: Molecular markers associated with outcome and metastasis in human pancreatic cancer

	PDACversus Metastases		Metastasesversus PDAC
KEGG Pathway^a	P-value	Upregulated genes^b	P-value	Upregulated genes^b
Wnt signalling	0.00969	FZD1, FZD10, WNT5A, CCND2
TGFβ pathway	0.00574	LTBP1, THBS4, MBPR1B	0.00100	SP1, PPP2R1B, ACVR1C

^a KEGG analysis was performed on respectively 278 and 80 genes upregulated in the PDAC and metastases samples using GENECODIS.
^b A selection of upregulated genes contributing to the pathways, is given.

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ISSN: 1756-9966

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