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Table 6 Cox proportional hazards regression model analysis of disease-free survival

From: Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patients

Variables (X)

Categories (different groups)

P value

OR value

95% CI for OR

Lower

Upper

Gender (X1)

Male (X1-0) vs. female (X1-1)

0.785

-

-

-

Age (X 2)

<60 (X2-0) vs. ≥60 (X2-1)

0.492

-

-

-

Smoking (X3)

0 (X3-0) vs. 0.1-40 (X3-1) vs. >40 (X3-2)

1.062

-

-

-

Histology (X4)

LAC (X4-0) vs. LSCC (X4-1) vs. SCLC (X4-2) vs. LCLC (X4-3)

0.908

-

-

-

Differentiation (X5)

Poor (X5-0) vs. moderate (X5-1) vs. well (X5-2)

0.013

1.514

1.090

2.103

T stage (X6)

T1-2 (X6-0) vs. T3-4 (X6-1)

0.769

-

-

-

Lymphatic invasion (X7)

Positive (X7-0) vs. negative (X7-1)

0.018

0.697

0.516

0.941

TNM (X8)

I-II (X8-0) vs. III-IV (X8-1)

0.001

0.532

0.370

0.765

Pleural invasion (X9)

Absent (X9-0) vs. Present (X9-1)

0.154

-

-

-

Annexin A1 (X10)

Low (X10-0) vs. moderate (X10-1) vs. high (X10-2)

0.000

4.723

2.703

8.253

Hsp90-beta (X11)

Low (X11-0) vs. moderate (X11-1) vs. high (X11-2)

0.000

2.923

1.857

4.601

Imaging (X12)

Central (X12-0)vs. ambient (X12-1)

1.600

-

-

-

Risk function:

H(t) = [h0(t)]e(0.415 X5 - 1.012 X7 - 0.631 X8 + 1.552 X10 + 1.073 X11)

  1. LAC, lung adenocarcinoma; LSCC, lung squamous cell carcinoma; SCLC, small cell lung cancer; LCLC, large cell lung cancer; Smoking, pack years of smoking. OR, odds ratio; CI, confidence interval.