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Table 6 Cox proportional hazards regression model analysis of disease-free survival

From: Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patients

Variables (X) Categories (different groups) P value OR value 95% CI for OR
Lower Upper
Gender (X1) Male (X1-0) vs. female (X1-1) 0.785 - - -
Age (X 2) <60 (X2-0) vs. ≥60 (X2-1) 0.492 - - -
Smoking (X3) 0 (X3-0) vs. 0.1-40 (X3-1) vs. >40 (X3-2) 1.062 - - -
Histology (X4) LAC (X4-0) vs. LSCC (X4-1) vs. SCLC (X4-2) vs. LCLC (X4-3) 0.908 - - -
Differentiation (X5) Poor (X5-0) vs. moderate (X5-1) vs. well (X5-2) 0.013 1.514 1.090 2.103
T stage (X6) T1-2 (X6-0) vs. T3-4 (X6-1) 0.769 - - -
Lymphatic invasion (X7) Positive (X7-0) vs. negative (X7-1) 0.018 0.697 0.516 0.941
TNM (X8) I-II (X8-0) vs. III-IV (X8-1) 0.001 0.532 0.370 0.765
Pleural invasion (X9) Absent (X9-0) vs. Present (X9-1) 0.154 - - -
Annexin A1 (X10) Low (X10-0) vs. moderate (X10-1) vs. high (X10-2) 0.000 4.723 2.703 8.253
Hsp90-beta (X11) Low (X11-0) vs. moderate (X11-1) vs. high (X11-2) 0.000 2.923 1.857 4.601
Imaging (X12) Central (X12-0)vs. ambient (X12-1) 1.600 - - -
Risk function: H(t) = [h0(t)]e(0.415 X5 - 1.012 X7 - 0.631 X8 + 1.552 X10 + 1.073 X11)
  1. LAC, lung adenocarcinoma; LSCC, lung squamous cell carcinoma; SCLC, small cell lung cancer; LCLC, large cell lung cancer; Smoking, pack years of smoking. OR, odds ratio; CI, confidence interval.