Figure 2

ROCs of probes that contribute to differentiation of nasopharyngeal carcinoma from other conditions. Combination of 6 genes with three genes appearing most frequently in all top-performing combinations LDLRAP1, PHF20 and LUC7L3. The additional three secondary genes have little NPC discrimination (ROC AUC: 0.51 – 0.77) but help suppress confounding factors. ROC AUC for each gene is listed in table. Dendrogram for the six-gene combination showing control samples dispersed throughout the “other” sample group with a separate cluster consisting mainly of NPC samples on the right. Heat map and clustering are based on results of 2-fold cross validation iterated 1000 times.