Table 3 Selected clinicopathological characteristics, gene profiling and survival data for patients harboring EGFR mutations
Age | Gender | Histology | Smoking status | Treatment Line | cMET (IHC) | EGFR (HIRSCH) | EGFR(FISH) | MET(FISH) | D7S486(FISH) | Best Response | PFS (months) | Survival (months) | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 37 | Female | AdenoCa | Smoker | 1st | ND | ND | ND | ND | ND | SD | 12.59 | 25.48 |
2 | 56 | Male | AdenoCa | Smoker | 4th | ND | ND | ND | ND | ND | PD | 2.39 | 4.23 |
3 | 76 | Male | Squamous | Smoker | 2nd | ND | ND | ND | ND | Deletion | PR | 11.67+ | 11.67+ |
4 | 64 | Male | AdenoCa | Non-smoker | 2nd | Negative | Negative | Negative | Negative | Deletion | NE | 8.52 | 29.51 |
5 | 76 | Female | AdenoCa | Non-smoker | 1st | Negative | Negative | ND | Negative | Normal | SD | 12.69 | 23.38 |
6 | 78 | Female | AdenoCa | Non-smoker | 1st | Negative | Negative | Negative | Negative | Normal | PR | 20.52 | 21.34 |
7 | 67 | Male | AdenoCa | Smoker | 2nd | Negative | Negative | Negative | Negative | Normal | PD | 3.25 | 28.49 |
8 | 62 | Female | AdenoCa | Non-smoker | 1st | Positive | Positive | Positive | Negative | Normal | SD | 40.20+ | 40.20+ |
9 | 47 | Male | AdenoCa | Smoker | 2nd | ND | ND | ND | ND | ND | NE | 4.00 | 4.00 |
10 | 43 | Female | AdenoCa | Non-smoker | 2nd | ND | ND | ND | ND | ND | PD | 2.56 | 2.85 |
11 | 63 | Male | Squamous | Smoker | 2nd | ND | ND | ND | ND | ND | PD | 2.26 | 12.49 |