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Figure 4 | Journal of Experimental & Clinical Cancer Research

Figure 4

From: Adenovirus-mediated delivery of CALR and MAGE-A3 inhibits invasion and angiogenesis of glioblastoma cell line U87

Figure 4

Transfection of Ad-CALR/MAGE-A3 attenuated the invasion ability of glioblastoma cells in vitro. Using matrigel coated invasion chambers, cell invasion ability was observed. The invading cells were fixed with cold methanol, and then stained with crystal violet. Representative microscopy images of the invasion assay are shown (×100). (A) - (D):Photomicrographs showing representative views of cell invasion assays. In the presence of Ad-CALR/MAGE-A3, the number of invading U87 (D) was smaller than those of U87 (A), U87/Ad-vector (B) cells and U87/Ad-CALR(C). Scale bars = 100 μm. (E): Bar represents the mean number of the cells per field. The invasion assay was consistent with the migration assay and showed that the transfection of Ad-CALR/MAGE-A3 attenuated the invasion ability of glioblastoma cells. *p < o.o5.

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