Table 4 Cox proportional hazard regression analysis of gender, age, histology, smoking status, EGFR mutation, WIF1 methylation and SFRP5 methylation for progression-free survival (PFS)
Variable | P value | Hazard ratio (95% CI) |
|---|---|---|
Smoking Status | 0.986 | 1.004 |
(smokers/nonsmokers) | Â | (0.615-1.640) |
Histology | 0.689 | 0.915 |
(adenocarcinoma/Nonadenocarcinoma) | Â | (0.592-1.414) |
Gender | 0.006 | 0.516 |
(male/female) | Â | (0.322-0.826) |
Age | 0.456 | 0.858 |
(<65/>65) | Â | (0.575-1.282) |
Lines of Treatment | 0.302 | 0.807 |
(first line/non-first line) | Â | (0.537-1.213) |
EGFR Mutation | 0.024 | 0.656 |
(mutation/wide type) | Â | (0.455-0.945) |
SFRP5 Methylation | 0.008 | 2.165 |
(methylated/unmethylated) | Â | (1.226-3.823) |
WIF1 Methylation | 0.224 | 1.804 |
(methylated/unmethylated) | Â | (0.697-4.674) |