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Table 1 Genes identified by SEREX

From: Autologous antibody to src-homology 3-domain GRB2-like 1 specifically increases in the sera of patients with low-grade gliomas

Gene name

Symbol

NCBI accession no.

Coding sequence

cDNA inserts of recombinant protein

amplified in breast cancer 1

ABC1

NM_022070

18.3563

 

anillin, actin binding protein (scraps homolog, Drosophilia)

ANLN

NM_018685

205.3579

 

ATP synthase, H + transporting, mitochondrial F1complex, beta polypeptide, nuclear gene encoding mitochondrial protein

ATP5B

NM_001686

106.1695

 

catenin (cadherin-associated protein), alpha-like 1

CTNNAL1

NM_003798

22.2248

 

CDV3 homolog (mouse)

CDV3

NM_017548

316.1092

 

centromere protein F, 350/400 ka (mitosin)

CENPF

NM_016343

175.9519

3553.4866

chromosome 14 open reading frame 145

C14orf145

NM_152446

172.3456

 

coagulation factor III (thromboplastin, tissue factor)

F3

NM_001993

124.1011

 

coiled-coil domain containing 86

CCDC86

NM_024098

56.1138

 

cyclin G1, transcript variant 2

CCNG1

NM_199246

135.1022

 

eukaryotic translation elongation factor 1 alpha 1

EEF1A1

NM_001402

64.1452

 

ferritin, heavy polypeptide 1

FTH1

NM_002032

236.787

 

ferritin, light polypeptide

FTL

NM_000146

200.727

 

heterogeneous nuclear ribonucleoprotein C (C1/C2), transcript variant 4

HNRPC

NM_001077443

219.1100

 

homeobox B2

HOXB2

NM_002145

121.1191

 

Homo sapiens mRNA for KIAA0146 gene, partial cds.

KIAA0146

NM_001080394

1.3218

 

macrophage migration inhibitory factor

MIF

NM_002415

98.445

23.561

myosin phosphatase-Rho interacting protein, transcript variant 1

M-RIP

NM_015134

57.3173

2194.3856

nucleolar protein 8

NOL8

NM_017948

304.3807

 

oral-facial-digital syndrome 1

OFD1

NM_003611

312.3350

 

postmeiotic segregation increased 1(S.cerevisiae)

PMS1

NM_000534

231.3029

 

retinoblastoma binding protein 8, transcript variant 1

RBBP8

NM_002894

332.3025

473.1274

ribosomal protein, large, P0, transcript variant 1

RPLP0

NM_001002

179.1131

433.1217

RNA export 1 homolog (S.pombe), transcript variant 1

RAE1

NM_003610

342.1448

 

serine/threonine kinase 3(STE20 homolog, yeast)

STK3

NM_006281

142.1617

 

SH3-domain GRB2-like 1

SH3GL1

NM_003025

107.1213

43.1615

synaptonemal complex protein SC65

SC65

NM_006455

289.1598

 

TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55 kDa

TAF7

NM_005642

741.1790

1578.2310

talin 1

TLN1

NM_006289

91.7716

5712…8187

transforming growth factor, beta-induced, 68 kDa

TGFBI

NM_000358

48.2099

1371…2691

unc-45 homolog A (C.elegans), transcript variant 2 or 3

UNC45A

NM_001039675

836.3625

1924.3471

  1. † cDNA inserts of positive clones were successfully expressed into proteins followed by ELISA.